Combinations ; - see below
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Novonorm | Novo-Nordisk | Phillips Pharmaceuticals Ltd. | 0.5mg | 30 | Tablet | per tablet | KES 1,112.00 |
| Novonorm | Novo-Nordisk | Phillips Pharmaceuticals Ltd. | 1mg | 30 | Tablet | per tablet | KES 1,164.00 |
| Novonorm | Novo-Nordisk | Phillips Pharmaceuticals Ltd. | 2mg | 30 | Tablet | per tablet | KES 1,214.00 |
| Premil | Beximco Pharma | Madawa Pharmaceuticals Ltd. | 0.5mg | 30 | Tablet | per tablet | KES 208.00 |
| Premil | Beximco Pharma | Madawa Pharmaceuticals Ltd. | 1mg | 30 | Tablet | per tablet | KES 230.40 |
| Repaglinide More info | |
|---|---|
| Mode Of Action | Carbamolylmethyl benzoic acid derivatives such as repaglinide act by stimulating the release of insulin from pancreas by closing ATP-dependent potassium channels in the membrane of the beta cells. This activity depolarizes the beta cells opening the calcium channels that leads to calcium influx and secretion of insulin |
| Drug Indication | Diabetic type 2. It used as monotherapy or in combination with metformin |
| Precautions | May cause resumption of ovulation in pre-menopausal anovulatory patients |
| Contra-Indications | Breastfeeding; type 1 diabetes; diabetes keto-acidosis; hepatic disorders. |
| Side Effects | Peripheral oedema; URTI; back pain; headache; anaemia. |
| Dosage | For patients previously untreated with a hypoglycaemic agent(s) and whose HbA1c is less than or equal to 8%: Initially 0.5mg orally (max. 16mg daily). For patients previously treated with a hypoglycaemic agent and whose HbA1c is greater than or equal to 8%: initially 1-2 mg (max. 16mg daily). It is taken 15-30 min before meal |
| Pregnancy Category | Category C |
| Pregnancy Category Description | Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible |
| Drug Category | DRUGS AFFECTING NUTRITION AND METABOLISM |
| Drug Sub-Category | Other medicines for treatment of diabetes |